Without the need for a central authority, blockchain technology allows for a decentralized and distributed ecosystem. Due to the application of cryptographic concepts, transactions are both safe and trustworthy. Due to the popularity of cryptocurrencies, blockchain technology has been extremely fashionable in recent years and has infiltrated many industries. Due to the need for a more patient-centric approach to healthcare systems, as well as to link disparate systems and improve the accuracy of electronic healthcare data, blockchain technology offers great promise in healthcare (EHRs). An examination of state-of-the-art blockchain research in the area of healthcare is performed in this systematic review. The goal is to showcase the technology's potential uses as well as the difficulties and future directions of blockchain research in healthcare. The article begins with a discussion of background material, followed by an explanation of the precise technique utilized in this research. The findings are then analyzed, with a bibliometric overview, an analysis of the collected data and its characteristics, and the results of a literature quality evaluation included. Finally, there is a discussion of the analyses' findings. According to the results, blockchain technology research in healthcare is growing, and it is mostly utilized for data exchange, health record management, and access control. The majority of research focuses on providing new structural designs as frameworks, structures, or models. Findings also indicate that most of the examined papers do not include technical information regarding the utilized blockchain components, and that most study does not provide any prototype implementation or implementation details. Even with a prototype implementation, no information regarding blockchain components is often provided.