Background: The number of visual impairments in the world is 285 million blind and 246 million having low vision. In India at least 2, 00,000 children have severe visual impairment or blindness and approximately 15,000 are in schools for the blind. Aim: Analyze the success of an audio drama-based teaching session for visually impaired kids about adopting a healthy lifestyle. Materials and methods: A quantitative research approach with Quasi-experimental one group pretest-post test design used in this study. Consecutive sampling technique was used to select the 50 samples. Structured questionnaire and audio drama was administered. After 1st week post-test was done and the findings of the study showed that out of 50 children‟s. Result: The calculated paired „t‟ test value for the domain personal hygiene (t=5.641, p=0.0001), oral hygiene (t=4.463, p=0.0001), sleep hygiene (t=4.399, p=0.0001), bathing (t=5.152, p=0.0001), hand hygiene (t=4.593, p=0.0001) and for overall (t=8.998, p=0.0001) was found to be statistically significant at p<0.001 level. The demographic variable religion ( 2 =11.078, p=0.026) and among children who are visually impaired, a statistically significant relationship between pre-intervention knowledge of healthy lifestyle practices at the p˂0.05 level and the other demographic factors had not demonstrated a statistically significant relationship with the pre-intervention level of knowledge regarding healthy lifestyle practice among visually impaired children. Conclusion: Teaching session adopting Audio Drama on knowledge about healthy lifestyle practice administered among children with visual impairment was found to be effective in increasing the knowledge in the post test.