Statistics is a division of arithmetic managing the gather, analysis, interpretation, presentation, and organization of information. Data are distinct pieces of information and is collected, observed, or created, for the purposes of analysis to produce original research results. There are many methods used to collect or obtain data for statistical analysis and it can be categorized as Census, Sample Survey, Experiment and etc. In the rapid growth of population and avaricious attitude of industries and residents are generated huge number of pollutions and diseases which affects our immune system at high level. Due to this reason, the health issues of people are uncontrolled and it becomes a big task to the government. So, many countries interested to influence the awareness among people through campaign, vaccination, and by conducting health camps. A vaccine is a biological preparation that provides an active acquired immunity to a particular disease. Vaccines led to the eradication of smallpox, Hepatitis, polio, measles, mumps, and chicken-pox which are deadly diseases in humans. In this paper, we analyze the people’s awareness about vaccination in and around Tamilnadu by using sampling techniques