IJFANS International Journal of Food and Nutritional Sciences

ISSN PRINT 2319 1775 Online 2320-7876

A Novel RP- UPLC Technique for the Simultaneous Estimations of Olanzapine and Samidorphan in Bulk and Tablet Dosage Form

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Y.Haritha Sri, , M Raghu Prasad ,Y. Rajendra Prasad ,L. Surendra Babu , M. Sri Vinay Reddy , D. Ganesh , G. Satya Narayanna , P. Venkata Prasad , S. Likhitha

Abstract

A convenient, precise, consistent, and robust quantitative approach was established for separation and simultaneous quantification of olanzapine and samidorphan in combination. The isocratic elution was attained by Hibar C18 (100 × 2.1mm, particle size 2µ) column at a flow rate of 0.3ml/min and temperature was maintained at 30°C.

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