Mucormycosis is an angio-invasive infection caused by the Mucorales fungus. Although it is an uncommon illness, it is becoming more common among immunocompromised individuals. Rhino-orbitocerebral, cutaneous, disseminated, gastrointestinal, and pulmonary forms may all be found. Despite the intensive therapy, there is an overall higher death rate. The primary goal and objective of this study were to provide an overview of Mucormycosis and its etiopathogenesis, as well as to discuss the fatality of rhinocerebral Mucormycosis and current advancements in diagnostic and therapeutic techniques. The presence of sporangiophores and rhizoid-like structures in his illustrations of the etiologic agent led to the conclusion that the infection was most likely caused by Lichtheimia corymbifera. More instances have been identified throughout time, and the disease's prevalence has risen.